SAMSARA THERAPEUTICS  Salary

WOOD CENTRE FOR INNOVATION STANSFELD PARK QUARRY ROAD OXFORD OX3 8SB UNITED KINGDOM

SAMSARA THERAPEUTICS
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SAMSARA THERAPEUTICS is looking for employees for positions:

research scientist

Education

  • phD

Responsibility

  • apply cellular and molecular techniques to assay cell biology pathways in iPSC-derived neurons from patients
  • study the mechanisms of action of autophagy modulators of the endolysosomal pathway in cellular models of neurodegenerative disease
  • conduct focussed compound evaluation for correction of disease phenotypes in endolysosomal biology
  • undertake maintenance culture and differentiation of iPSC lines into neuronal populations such dopaminergic neurons and motor neurons
  • generate robust and reproducible experimental data by following best lab practices and guidelines
  • maintain accurate records of experiments and data
  • contribute to wider project planning, including ideas for new research projects
  • determine the most appropriate methodologies to test hypotheses and identify suitable alternatives if technical problems arise

Requirements

  • hold a PhD / DPhil in molecular or cellular biology
  • extensive experience in cell culture, preferentially in stem cell -derived models of neurological disorders
  • skilled with performing cellular assays such as high-content imaging, electrophysiology, multi-electrode arrays, calcium imaging
  • skilled in molecular biology techniques
  • good track record of peer-reviewed publications
  • skilled with analysis and interpretation of research data
  • able to work independently to plan projects and experiments
  • able to meet deliverable and reporting deadlines