laboratory technician
Responsibility
- the successful candidate will be responsible for the maintenance of tissue culture cell lines used for recombinant expression in mammalian cells and insect cells
- collaborate with the lab manager and site operation manager to maintain sufficient stocks of media, flasks and other TC/general lab consumables
- generate Baculo/BacMam viral stocks and carry out virus amplifications for large scale-ups
Requirements
- A degree or equivalent combination of training and experience in a life sciences setting or other relevant area
- familiarity and/or previous exposure to large-scale protein production workflows in a pharmaceutical /Biotech laboratory
- extensive practical experience in a sterile culture techniques and recombinant expression systems
Show more +36 - fundamental knowledge of biochemical techniques and familiarity with protein purification techniques and equipment
- cell culture experience including general maintenance of mammalian cells
- the high resolution of our biophysical platform offers an unprecedented advantage in the detection of drug leads
- excellent knowledge of upstream and downstream processes of recombinant protein expression
- experience with suspension cultures of mammalian/insect cells
- technical laboratory support in a scientific or bio-medical environment
- the company vision is to build an integrated drug discovery company, with the ambition to develop and ultimately commercialise our products
- robust skills in standard molecular biology techniques, such as generation, handling and amplification of plasmids
- experience with Baculo- /BacMam or Lentiviral expression systems
- stock management control and maintenance of inventory levels
- has the ability to work flexibly within a team as well as being highly self-motivated and work independently
- experience with large-scale transient transfection methods
- well-organised, demonstrable ability to prioritise and manage time and tasks effectively
- OMass Therapeutics is a drug discovery company, applying its unique OdyssION™ technology platform, which comprises novel biochemistry techniques, next-generation native mass spectrometry, and custom chemistry, to discover small molecule therapeutics for rare diseases and immunological conditions
- northpond Ventures, and Sanofi Ventures. This is an excellent time to join our dynamic growing company
- demonstrates good problem-solving skills to overcome technical challenges
- experience in maintaining reagents/media/consumable stocks
- ability to diagnose problems and develop solutions, both independently and as part of a team-based approach
- with state-of-the-art laboratories OMass is able to perform high resolution native mass spectrometry measurements, pharmacological studies, chemical computational analysis and more recently high-resolution structure determination, including crystallography and cryo
- has excellent organizational and time management skills as well as the ability to work to strict deadlines
- good numeracy and communication skills
- EM. Our fully flagged protein production suite has expression capabilities in mammalian, insect and bacterial cell lines and supports our internal drug development program
- job Type: Full-time, Permanent
- EM. Our well-equipped pharmacology laboratory is crucial for reporting ligand activity in the cell, and has a center role from hit ID to lead optimization
- the company was founded by Professor Dame Carol Robinson to leverage her pioneering work in native mass spectrometry, in studies of dynamic protein assemblies, to characterise challenging drug targets including membrane proteins
- we are looking for a scientist with extensive experience in culturing cells for recombinant protein expression
- has strong communication skills, both written and verbal
- location: Oxford
- OMass Therapeutics values diversity and is committed to equality of opportunity, we also have full responsibility to ensure that all employees are eligible to work and live in the UK
- the successful candidate will possess extensive experience in culturing and generating mammalian cell lines and in supporting general lab operations
- ability to work flexibly within a team as well as work independently
- computer literate and ability to familiarise with different IT systems
- proactive and flexible attitude to problem solve and respond to changing demands
- the company offers a collaborative and innovative environment for a well-suited candidate to become an integral part of our future vision
- headquartered in Oxford, UK, OMass has raised over $150M from a top-tier international investor syndicate, including Syncona, Oxford Science Enterprises, GV
- job Types: Full-time, Permanent
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